Sickle Cell Disease:
-Sickle Cell Disease is caused by a mutation that affects the hemoglobin
-In a person with sickle-cell disease, red blood cells can become sickle-shaped instead of round
-The red blood cells of people with tbe disease have a sickle, or crescent, shape
-Sickle-shaped red blood cells cannot carry as much oxygen as normal cells and also clog blood vessels
-A person with one normal allele and one sickle cell allele usually does not have symptoms of the disease
-Sickle Cell Disease is caused by a mutation that affects the hemoglobin
-In a person with sickle-cell disease, red blood cells can become sickle-shaped instead of round
-The red blood cells of people with tbe disease have a sickle, or crescent, shape
-Sickle-shaped red blood cells cannot carry as much oxygen as normal cells and also clog blood vessels
-A person with one normal allele and one sickle cell allele usually does not have symptoms of the disease
Down Syndrome :
- Down Syndrome - A congenital characterized by moderate to severe mental retardation, slanting eyes, a broad short skull, broad hands with short fingers, and trisomy of the human chromosome numbered 21
-Down Syndrome results when abnormal cell division involving chromosome occurs
-Most of the time, Down Syndrome isn't inherited
-If the father carrier of Down Syndrome, the risk is is about percent
-If the mother is the carrier of Down Syndrome, the risk is between 10 and 15 percent
- Down Syndrome - A congenital characterized by moderate to severe mental retardation, slanting eyes, a broad short skull, broad hands with short fingers, and trisomy of the human chromosome numbered 21
-Down Syndrome results when abnormal cell division involving chromosome occurs
-Most of the time, Down Syndrome isn't inherited
-If the father carrier of Down Syndrome, the risk is is about percent
-If the mother is the carrier of Down Syndrome, the risk is between 10 and 15 percent
Hemophilia :
- Hemophilia is caused by a defect in or a lack of clotting factor
- If a man with hemophilia have a child, his sons will not have hemophilia, but his daughters will be all carriers
-Some children born with hemophilia have no family history of the disease because genetic changes can occur for no reason
-People cannot "catch" hemophilia, they are born with it
Triple X syndrome :
-Triple X syndrome - an abnormality resulting in an extra X chromosome in some females
-Triple X Syndrome is usually caused by malformation of an egg or sperm cell, or by an error early in embryo development
-Many women have a few or no symptoms like delayed development, learning disability, or speech delay in a child
-In most cases, no treatment is required
Duchenne muscular dystrophy :
- An inherited disorder of progressive muscular weakness, typically in boys
-Girls can be carriers and mildly affected, but the disease typically affects boys
-There is no cure, but physical therapy, and medications
-symptoms include frequent falls, trouble getting up or running, waddling gait, big calves, and learning disabilities
-Duchenne muscular dystrophy affects 1 in 3600 boys, which results inmuscle degeneration and premature death